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Primary vitrectomy for degenerative and tractional lamellar macular holes: A systematic review and meta-analysis

2021

Purpose To assess the efficacy of vitrectomy in degenerative and tractional lamellar macular holes (LMHs) by meta-analysis of published studies. Methods PubMed, Medline and Embase databases were searched up to May 2020. Included cohorts were divided into three groups: degenerative LMH group, lamellar hole associated epiretinal proliferation (LHEP) group and tractional LMH group. LHEP is likely to be associated with degenerative LMHs, but less commonly could be associated with mixed LMHs. To reduce risk of possible misclassification bias, eyes with LHEP which could not have been precisely classified by the authors, were included into the LHEP group. The primary outcome was to investigate th…

0301 basic medicineVisual acuitygenetic structuresVisionmedicine.medical_treatmentVisual AcuitySocial SciencesVitrectomyDatabase and Informatics MethodsMathematical and Statistical Techniques0302 clinical medicineVitrectomyMedicine and Health SciencesPsychologyMedicineDatabase SearchingMacular holeMultidisciplinaryIncidence (epidemiology)StatisticsQOphthalmic ProceduresRMetaanalysisResearch AssessmentMeta-analysisPhysical SciencesMedicineSensory PerceptionAnatomymedicine.symptomResearch Articlemedicine.medical_specialtySystematic ReviewsScienceSurgical and Invasive Medical ProceduresResearch and Analysis Methods03 medical and health sciencesOcular SystemOphthalmologyHumansStatistical Methodsbusiness.industryPrimary vitrectomyCognitive PsychologyBiology and Life SciencesHumans; Retinal Perforations; Visual Acuity; VitrectomyRetinal Perforationsmedicine.diseaseConfidence intervaleye diseases030104 developmental biology030221 ophthalmology & optometryCognitive ScienceEyesPerceptionVisual gainbusinessHeadMathematicsNeuroscience
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